At the heart of Alkemii is Pi-7 Complex™ - our patent-pending proprietary blend of marine algae-derived polyphenols and polysaccharides. Created by Alkemii, Pi-7 Complex™ was developed to bring together marine bioactives, follicle-focused research and a new approach to hair longevity. Tested beyond the bottle. Pi-7 Complex™ was independently tested ex vivo on isolated human hair follicles to measure biological signals associated with follicle activity, growth signalling and cellular renewal. This testing looked at key biomarkers connected to the hair follicle environment, including markers associated with growth signalling, cellular proliferation and renewal.
What are biomarkers?
In hair science, biomarkers can help show whether a formula is interacting with pathways associated with follicle activity, growth signalling and renewal.
Biomarkers are measurable biological signals that help scientists understand how cells or tissues are responding.
Biomarker results -->
+533% WNT5A
A growth-related signal linked to the hair follicle’s active growth environment. Observed in the hair bulb versus the excipient control.
Up to +96% IGF-1
Associated with follicle function, cell survival and the hair growth cycle. Observed increases included +96% in the hair bulb and +86% in the lower root sheath.
+85% Ki67
A marker linked to active cells within the hair follicle, an important sign of follicle activity. Observed in the lower root sheath versus the excipient control.
Results observed in independent ex vivo laboratory testing on isolated human hair follicles. Individual results may vary.
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Marine algae-derived bioactives
Marine algae are rich in bioactive compounds that can help support a modern, science-led approach to haircare and hair longevity.
Pi-7 Complex™ is built around marine algae-derived polyphenols and polysaccharides.
Why Pi-7 Complex™ matters
Alkemii was created to go deeper than surface-level haircare.
Pi-7 Complex™ gives the Miracle Roller its scientific heart:
a patent-pending marine complex independently tested in a laboratory setting on isolated human hair follicles.
